Piperine-hydroxybenzoate as phytochemistry antiosteoarthritis combination: Structural, solubility, and in vivo antiinflammatory study

Piperine-hydroxybenzoate as phytochemistry antiosteoarthritis combination: Structural, solubility, and in vivo antiinflammatory study

Blog Article

This study discusses the composition and structure determination of a kicker pro comp 10 new multicomponent system from antiinflammatory natural ingredients, consisting of piperine (Pip) and 4-hydroxybenzoic acid (HBA), named Pip-HBA.In addition, this research studied its solubility and anti-inflammatory activity.After screening the stoichiometric proportions, this multicomponent system formation reaction was carried out using the solvent-dropped grinding and evaporation methods.Characterizations using solid analysis including differential scanning calorimetry (DSC), powder X-ray diffractometry (PXRD), and Fourier transform infrared spectroscopy (FTIR), confirmed the formation of Pip-HBA.These multicomponent systems showed different thermograms and diffractograms.

Furthermore, the FTIR spectrum of truvisionhealthftp.com Pip-HBA multicomponent system differs from the physical mixture and its constituent components.Single crystal diffractometry (SCXRD) determined Pip-HBA to be a new multicomponent system structure in three dimensions.Pip-HBA showed increased solubility and anti-inflammatory activity compared to single piperine.Therefore, Pip-HBA multicomponent system has quite potential for further preparation development.